Antisperm Antibodies Linked To Infertility In Men

Infertility is an issue that many men find it hard to discuss. It is the question of their virility and they do not want to be a laughing stock amongst their peers or friends. The reasons for infertility in men might vary from one person to another. Antisperm antibodies can only be one of the root causes of this issue. These are cells that work against the health sperm thereby destroying them in the process.

How Antisperm Antibodies Affect Fertility

The human body as we know is protected by our immune system. When the body is fit and healthy it produces protective proteins called as antibodies. These antibodies fight against viruses and bad bacteria thereby protecting us from diseases and infections.

Antisperm antibodies invade the sperm by attaching themselves to it. This in turn reduces the sperm motility. When the sperm motility is reduced, it becomes difficult for the sperm to fertilize the eggs. In some cases, these antibodies might even force the sperm to form clusters or move in slow circular motion instead of forward.

In simple words, antisperm antibodies can either kill the sperm or prevent the motion of the sperm. Many of the doctors generally test couples for such issues before recommending the right medication to cure infertility.

What Causes Antisperm Antibody and Who Can Get Them

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The sperm in men are generally protected by a lining known as the blood testes barrier. The main objective of this barrier is to prevent the cells in your immune system to mix with the sperm cells thereby destroying them in the process. When this barrier is breached or compromised due to injury or surgery, then it can give rise antisperm antibody.

Another reason for this condition to occur might be due to vasectomy, biopsy or testicular cancer. Antisperm antibody is not only limited to men. It can occur in women also. Women might suddenly develop allergic reactions to semen

Antisperm antibodies are relatively common in both men and women. While 1% of fertile men are said to have these in their bloodstream, the chances are 10% in infertile men. In women, this risk is about 5% giving their various infertility issues.

Tests and Treatment for Antibody Antibodies

Depending on your medical condition and history there are a number of tests that you might need to take for detecting the presence of antisperm antibodies in your body. Women might have to undergo blood tests or a post coital test, whereas men might have to take the sperm tests to analyze the antisperm antibodies.

Couples facing infertility issues due to antisperm antibodies can be treated through corticosteroids. These help in decreasing the production of antisperm antibodies in the body. Similarly many doctors even take the help of intrauterine insemination that helps the sperm to enter the cervical mucus.

Another successful option available for couples would be the In- Vitro fertilization. In this treatment the sperm is directly injected into the female eggs without the sperm having to pass through the fallopian tubes.

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